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Weight loss decreases risk of breast cancer


A new research has shown that women with a mutation in a particular type of gene that predisposes them to breast cancer, are 65 percent less likely to develop the disease, if they shed weight between 18 and 30 years of age.

According to the study published in the journal Breast Cancer Research, young women with this genetic predisposition should avoid putting on weight in early adulthood, especially if they plan to have children.

Steven Narod from the University of Toronto and colleagues studied two groups of women, all of whom had a mutation in one of the breast cancer susceptibility genes BRCA1 and BRCA2. The first group had been diagnosed with breast cancer while the second group had not.

Each member of the first group was paired up, or ’matched’, with a woman from the second group who was the same age, carried a mutation in the same gene and lived in the same country.

By comparing the two groups, the researchers could identify the relationship between the incidence of breast cancer before the menopause in women at risk, and weight at 18, 30 and 40 years of age.

Their results show that, for women who have a mutation in BRCA1, weight loss of at least 10 pounds was associated with a 65 percent reduction in cancer risk between ages 30 and 40, said he researchers. (ANI)

Washington | August 21, 2005 12:21:21 PM IST

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